https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517983/#:~:text=Overall%2C%2022.0%25%20(95%25,did%20not%20use%20a%20statin.

This blog came on the heels of several patients reporting a common problem in the same week: Intense persistent pain in their legs and quads from taking statin medications. The problem is well known, but often underreported by patients and not always recognized by the prescribing physician. Differential diagnosis of neuro-musculoskeletal pain can be challenging in the population most often taking statins. But in the context of our chiropractic practices, we always need to take statin side effect as a possible reason for persistent pain, especially in the lower extremity. This can mimic or compound pain from other areas (hip and knee arthritis, bursitis, lumbar nerve pinching) and limit how much a patient can recover.

The solution can be just as complex as isolating the problem. Patients needs to inform themselves on risk benefit ratios of any medications and non pharmacological approaches to improving abnormal lipid profile.