Headaches and the hidden sources of MSG

As usual it takes a couple cases back to back to throw me into writing an overdue blog. In this case, some mysterious atypical migraines for which the patient could not figure out any trigger.

There is a lot of confusion about MSG and the reactions that people can get from it.

First, probably helpful to review what MSG actually is and what it does. MSG stands for monosodium glutamate. It's both a naturally occurring substance of food aging and fermenting, as well as a strong chemical additive that is added to a large variety of foods to enhance taste, palatability, and the desire to eat more processed foods. The glutamate part is also an excitatory neurotransmitter, which when combined to the monosodium bit makes it very more apt to cross the blood brain barrier and dump into your central nervous system where it will act as a strong stimulus to brain cell electrical firing.

Patients can have varying degrees of sensitivity to MSG. For some people, they might not know the difference if they have a small amount and have no particular sensitivity. For other patients, there reaction ranges from mild to severe. Patients who are more likely to have a severe reaction to MSG are people who have blood brain barrier weakness, such as patients with previous concussion, certain medications, and certain type of chronic infections and autoimmune tendencies. For those people, the MSG can cross the blood brain barrier, create a sort of electrical storm in the brain that drains the battery of brain cells, and lead to widespread random brain activities that can manifest as migraine headaches, with a lot of other unusual symptoms such as pain, tingling in their body, and a lot of autonomic symptoms such as nausea and G.I. upset. For some people the MSG induced symptoms can last a few days.

MSG actually does occur in very small amounts in natural foods that have been aged and fermented in particular. However that is rarely the culprit. MSG used as a food additive occurs in much larger amounts than what people would typically see in unaltered foods.

Where the real problem comes in is that MSG is often not labeled as MSG in food. Below is a good reference website that lists all the names under which MSG can be labeled, making it a real challenge for patients to pinpoint MSG as 1 of the triggers to their headaches. I have several patients who have printed the list in a wallet size cards that they carry with them when they shop. To give you an example of common MSG additives:

• Autolyzed yeast

• Autolyzed yeast protein

• Carrageenan

• Pectin

• Sodium caseinate

• Soy isolate

• Soy sauce

• Textured protein

• Vegetable extract

• Yeast extract

• Yeast food

https://www.prevention.com/food-nutrition/a20472934/other-names-for-msg/

SITTING IS THE NEW SMOKING

https://jamanetwork.com/journals/jamacardiology/article-abstract/2793521

There are so many important topics to try to keep up in the blogs that I haven't talked about this one for a while and it's overdue. Especially in a post-pandemic area were still many people have remained working from home part or full time, and even the small amount of physical activity involved in getting in the vehicle and commuting to a workspace has been eliminated for some folks.

The data on the harmful impact of prolonged sitting keeps mounting, and its metrics on adverse health outcomes is becoming increasingly measurable, in the same way that we can measure adverse impact of smoking in terms of daily cigarettes. This most recent study published by JAMA puts some numbers on the problem and they are sobering. For the people who pride themselves of not smoking, remember that if you consistently sit eight hours a day without some balancing physical activity outside of that, you are no better off than someone puffing a pack a day.

There are a few simple strategies that you can work on to mitigate the impact of Fort sitting.

– Whenever possible, consider having a sit stand workstation. The availability of inexpensive desktop retrofits is becoming widely available. Many employers are also honoring requests of employees to retrofit their workstation with us it's an option if not alright available. In the end, for a few hundred dollars you can probably make it happen even if your employer is not cooperating. Your health is on the line. You do not need to be standing your whole workday but try to aim for 1/3 to 1/2 of the total time

– Whenever take frequent standing and walking breaks. To keep yourselves accountable, use a fitness tracker to see what your total sitting time is. Ideally you want to be below four hours of workday.

– If you are in a situation where avoiding prolonged eight hour workday sitting is impossible, make sure to make up with it with vigorous balancing physical activity outside of that timeframe. Walking, higher intensity aerobic exercise. Prolonged sitting is especially associated with poor cardiovascular outcome, possibly because of the stress it physically puts on our arterial system.

What is a contrecoup sprain?

Growing up speaking French as a 1st language I enjoy lording it over people with little French inspired vocabulary from time to time. However the term"contrecoup" is not just a futile exercise of language, but something very relevant at this season.

The original term "contrecoup injury" is meant to describe a type of concussion whereby the brain is injured on the opposite side of the impact, and the result of the soft brain hitting the hard skull bone during an acceleration deceleration impact. However I have been using the term " contrecoup" a little more broadly to define a scenario whereby the injury can be on the opposite end of the point of impact.

The most common scenario I run into is when a patient falls on their buttocks, and finds themselves with a cervical injury. This happens quite a bit when we slip on the ice at this season. The patient is originally very concerned about bruising and soreness at the point of impact, but are really baffled when they wake up a few days later with massive cervical pain and headaches although they did not hit their head or neck on the ice. The force transmitted from the pelvis to the neck and head during the deceleration phase of your hind end hitting the ground is in the 3 digit, and it's virtually a mini whiplash. The moral of the story is that because you did not hit your head doesn't mean you did not injure your neck.

Abdominal Massage For Chronic Constipation

Chronic constipation is one of those health scourges nobody likes to discuss with friends over coffee. It significantly impacts your quality of life, it's a very unglamorous problem, and conventional healthcare does not offer a lot of solutions (and to be fair even good integrative healthcare sometimes struggles to achieve that as well.)

Once medical reasons for chronic constipation have been ruled out, and they are quite few of them actually, patients are instructed to follow some basic self-care practices to improve transit time. By the time people reach us, they have already improved their hydration, increased their fiber intake, and their aerobic activity to no avail. They walk in the door with a diagnosis of "functional constipation" which basically means they are chronically constipated and we have no idea why.

This blog entry is not meant to be a comprehensive review of the algorithm to workup chronic constipation, since that would take 20 pages, but to review one particular aspect of managing functional constipation that most patients have never been exposed to: the effectiveness of self directed abdominal massage to improve normal bowel muscular activity. The technique is quite simple, can be taught in about 20 minutes, is painless, and only takes a few minutes a day. What is even more remarkable is that a recent double-blind controlled clinical trial showed it to be remarkably more effective than placebo and other conventional methods.

In the video Anne demonstrates the basic technique you can use on yourself. I highly recommend however that you make an appointment with a massage therapist for 30 minutes to practice the method on yourself so you feel confident that you will get the benefit of doing it at home.

https://www.youtube.com/watch?v=BykR20PmdQs

https://pubmed.ncbi.nlm.nih.gov/35554601/

"Grandparent Syndrome"

I want to bring to peoples’ attention a pattern that has been crossing my radar increasingly over the last few months. I am nicknaming it “Grandparent Syndrome”. It simply consists of a patient coming into the clinic and saying something to the affect of: “I babysat my grandchild/children over the weekend, and boy, I hurt.” I am not saying this is a new thing by any means, but my guess is that many grandparents took a hiatus from babysitting over the Covid years. Now many grandparents are jumping back into the swing of things and they are doing things that are certainly out of their normal activities of daily living.

I want to highlight a few of the likely stressors that the average grandparent is going to face when babysitting. One is simply that when you take care of children, your attention is mainly focused on them; this can make it more difficult to notice when you are getting tired, or are holding a muscular strain beyond the comfort point. If you can regularly take a moment to direct your attention toward your body, you may be able to spot muscular tension before it gets to a high pitch.

The second thing is to be aware of positioning. For example, you are holding a 5 month old child. You unconsciously prefer holding on the right side of you body. You then might spend 2 hours with your right shoulder medially rotated and your head tilted right and downward as you look at the infant. A better solution is to hold the baby on both sides. This will still be a strain, but it will be divided between the two sides, and you will avoid a one sided holding pattern. This may seem like a silly addendum, but if you like to lay down with an infant, take a little time to have a comfortable pillow. Remember, you might be in that position for a while!

The last thing is for grandparents with grandchildren in 2-4 year age range. Grandparents are expected to be a soft touch as far as doing what the grandchildren want. (I remember this very well from my young days). What you should keep in mind is whether or not you can pick up and hold an older grandchild comfortably. Maybe for some grandparents, they can comfortably hold an older child for a little while. Others may not be able to pick up a child without aggravating a shoulder, hip, arm, etc. My recommendation for those who cannot hold a child with comfort is to harden their hearts, and modify their response to the child’s wish. Maybe you can sit with them on a couch or come down to their level. Or hold them only for the amount of time it is comfortable.

The overall takeaway is to bring some awareness to your babysitting, so that you can enjoy your grandchildren without causing undo Grandparent Syndrome.

Vagal Autonomic Breathing Exercise

https://www.youtube.com/watch?v=aXiXCK0U08c

This is probably one of the most important videos I have recorded, and a long time coming. We often tell people they need to breathe more and better but we don't give them specifics about what constitutes beneficial breathing. This particular exercise is very specifically geared to improve parasympathetic autonomic function, also known as vagal breathing, to try to counteract the chronic fight and flight response that most of us are stuck in. It is especially helpful for people trying to have easily accessible tools to break anxiety.

Shining some light on Seasonal Affective Disorder

For some people the winter season is more than a little crabbiness about cold weather, shoveling, and post holiday bulging waist. It can be a time of low moods, at times nearly debilitating, that last several months and leads to a sense of dread at the end of the fall. It's a complex disorder and this blog is not meant to be a comprehensive review of all that is available but to give you pointers on some key interventions that when taken together can make the next one month more manageable and possibly enjoyable.

Seasonal affective disorder, later referred to as SAD, is triggered by a combination of seasonal external factors (change in outdoor temperature and light cycles), compounded by our response to those external factors, both internally in our own biology as well as in our habits and self-care. I'm going to address interventions in each category.

Change in light pattern: Outdoor light is a powerful regulator of our sleep-wake cycle and moods, and is at its lowest level between October and March, at the same time as our lower temperatures in the northern hemisphere. Outdoor light has a spectrum of colors that changes from morning to noon, with a spectrum that increases wakefulness prior to noon, and gradually decreases wakefulness in the evening with warmer hues. For a lot of people with day jobs, this means that your brain may never be exposed to the natural cycle light for several months out of the year, with significant disruption to normal wake sleep mood regulation. To make it worse, light emitted from indoor traditional light sources, and especially from technology screens, tends to be blue dominant, which is stimulatory and blocks the release of melatonin (a hormone triggered at the time of initiation of sleep) consequently setting off a cascade of dysregulated wakefulness and leading to low mood. If getting out to be exposed to natural light prior to noon is not routinely available to you during the winter months, consider using a light therapy box for 20 minutes earlier in the morning most days of the week (nowadays those lights can easily fit on your desk or on your kitchen counter wherever you may be for an hour in the morning), and get yourself a pair of blue filtering glasses (nonprescription, can be available from any online retailer) to use starting midafternoon on, to protect your vision from the suppressive effect of your computer screen on melatonin. Maintaining a normal melatonin cycle is essential to maintaining normal moods during the winter.

Change in temperature pattern: Exposure to seasonal cold can have a ripple effect on blood circulation and our own physical activity level. In particular, our brain has a powerful ancestral mechanism to protect core organs from hypothermia, which are still somewhat active even for modern creatures living with indoor heat. This can lead to slightly decreased general blood perfusion in our extremities (including our head, which is the hardest organ to reach for circulation going uphill against gravity). In addition, for a lot of people there is a general decrease in physical activity and cardiovascular endurance during the winter month, as our level of the day to day movement is less when cooped up inside. This is especially a problem when compounded by the fact that many people do not have a robust exercise routine to transition to in the winter. This leads to decreased blood circulation to the brain, which is a big driver for decreased general metabolic activity of normal neurotransmitter and hormonal balance. I always encourage people to be accountable to themselves by using a fitness tracker in the winter to see if they meet physical activity standards (10,000 steps or equivalent). There are lots of options for exercise that can be done from the comfort of your home, refer to other blog entries on that subject.

Change in vitamin D metabolism: Unless you have a consistent vitamin D3 supplementation during the winter months, you're very unlikely to have enough outdoor skin exposure to produce your own. Everyone metabolizes vitamin D a little differently so there is not a hard and fast rule about how much to take but the range is anywhere from 2000 IUs – 5000 IUs, with the goal of maintaining serum levels between 30 – 50. Remember that multiple supplements used for other purposes than straight vitamin D3 supplementation will have some low level of vitamin D3 added so make sure you look at the total amount of vitamin D3 you may be ingesting. Vitamin D3 serum levels has been repeatedly associated with chronic mood disturbances.

Change in eating patterns: The holiday season in particular can be a real minefield for people to maintain a diet containing necessary nutrients for adequate mood modulation (adequate protein, antioxidants, clean essential fatty acids, fiber), opening the door for high sugar food and a lot of glycemic spikes. This can be another major contributing factors to poor mood control. Knowing that you moods can be so negatively impacted by your food choices in the winter should hopefully be an encouragement for people to try to stay on the proverbial wagon, and if splurging, keep it to a few days.

For people who feel that they have implemented all the self-care methods available to them to control seasonal affective disorder but not achieving satisfactory results, it may be beneficial to test for your individual hormonal and neurotransmitter imbalances, in particular the role of melatonin, cortisol, dopamine, serotonin, and glutamine. This can give you much needed insight and specifically and individually managing your own imbalances. https://www.zrtlab.com/test-specialties/neurotransmitters/

Armaid: home self care for chronic soft tissue pain of the arm and wrist

https://www.youtube.com/watch?v=0SfmM1BRdi8

I have always known to be judicious to the point of slightly skeptical when it comes to a lot of self-care tools that patients want to use at home for relief of a variety of neuromusculoskeletal conditions. Many of them have come and gone after a brief surge in popularity driven by intense social media marketing. I am a frequent thrift store shopper and invariably there are miscellaneous home goods that look like a graveyard of various such tools that were once the hottest item on the market.

There are of course notorious exceptions to that, and the Armaid and several offbrand similar devices fit in that category. It's a relatively simple tool designed originally by rock climbers to perform some specific deep self massage and soft tissue release of the elbow and down primarily. Many of our patients have to engage in activities, whether professionally or recreationally, that place high repetitive demands on wrist and finger flexor muscle groups, with high likelihood of setting off a chronic repetitive injury cycle. As a supplement to in office treatment, I will often recommend the ongoing use of the Armaid for patients to control and stay ahead of escalating soft tissue injuries. We have a loaner unit at the office that I will send home with patients after training them specifically on how to use it for their particular condition. If patient find it successful, we will direct them to purchase their own unit. The cost is still below $100, paying for itself many times over in saved in office visits.