https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690966/
I had tagged this article a few years ago already, but never got to post it for a variety of reasons. I am getting back to it now, as the topic of Alzheimer’s dementia has become more vivid in my extended family, as in many of yours.
There is still so much we do not know about this ugly disease, and meaningful drug therapies are not in the near future (if you look at the “new Alzheimer’s drugs that were approved, you can understand the controversy of the public health agency decision when you review the abysmal true beneficial effects at a price tag of 60 K per year). However we are starting to chip away at modifiable risk factors. Some are known (diet, cardio exercise), some are coming out slowly. Among risk factors that do not get the nod they need are the medications that increase the risk, especially the common daily medications that people think of as safe. We need to revisit our risk tolerance to those in light of the research, and this piece of research makes a stunning case for the fact that NSAID use in the senior population may raise the risk of developing Alzheimer’s. Take note for yourself and your loved ones and consider doing something more restorative than masking the pain with another over the counter pill.